O le Fusi ma le Auala: Galulue, Felagolagomaʻi ma Manumalo
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4-Nitrophenyl Beta-D-glucuronide CAS:10344-94-2

4-Nitrophenyl Beta-D-glucuronide ose vailaʻau faʻapipiʻiina e ala i le faʻapipiʻiina o le kulukose mole i se vaega 4-nitrophenyl e ala i se fesoʻotaʻiga glycosidic.E masani ona faʻaaogaina e fai ma sui i suʻega enzymatic e iloa ai le i ai ma le gaioiga o le β-glucuronidase, o se enzyme o loʻo aʻafia i le metabolism o vailaʻau eseese ma xenobiotics i mammals. ma le 4-nitrophenyl vaega, e mafua ai le tuʻuina atu o le 4-nitrophenol, lea e mafai ona iloa spectrophotometrically i le 400-420 nm.Ole tali ole enzymatic e maua ai se fua fa'atatau ole gaioioiga β-glucuronidase ma e masani ona fa'aaogaina e fai ma meafaigaluega ile su'esu'eina o vaila'au, su'esu'ega oona, ma su'esu'ega ile falema'i.


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Fa'aoga ma A'afiaga

Su'esu'ega ole gaioiga ole β-glucuronidase: 4-NPBG e masani ona fa'aaogaina e fai ma mea e fai ai le chromogenic e iloilo ai le iai ma le gaioiga o le β-glucuronidase i fa'ata'ita'iga olaola eseese.O le enzyme e faʻamavaeina le glycosidic bond o le 4-NPBG, e maua ai le 4-nitrophenol, lea e mafai ona fuaina e faʻaaoga ai le spectrophotometry.

Suʻesuʻega o le metabolism: Talu ai o le β-glucuronidase e taua tele i le metabolism o vailaʻau ma xenobiotics, e mafai ona faʻaaogaina le 4-NPBG e iloilo ai le gaioiga o lenei enzyme i suʻesuʻega o le metabolism.E fesoasoani i le malamalama i le lautele ma le kinetics o le glucuronidation reactions, lea e taua mo le kilia o fualaau faasaina ma bioavailability.

Su'esu'ega Toxicology: O nisi o vaila'au o'ona e mafai ona fa'afefeteina ma fa'aulu i le tulaga o glucuronide conjugates.I le faʻaaogaina o le 4-NPBG e fai ma sui, e mafai e tagata suʻesuʻe ona suʻesuʻeina le gaioiga o le β-glucuronidase i totonu o masini eseese poʻo laina telefoni e iloilo ai le ono afaina poʻo aʻafiaga leaga o faʻalapotopotoga.

Faʻataʻitaʻiga faʻapitoa: O le fuaina o le gaioiga o le β-glucuronidase e faʻaaoga ai le 4-NPBG e mafai ona faʻaogaina i totonu o falemaʻi e faʻamaonia ai nisi faʻamaʻi poʻo tulaga.La'asaga le masani po'o le gaioiga o le β-glucuronidase e ono fa'ailoa mai ai ni fa'afitauli fa'apitoa, fa'aletonu o le ate, po'o le kanesa.

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Fa'aputuga o oloa:

6892-68-8-3

Fa'amatalaga Faaopoopo:

Tulaga C12H13NO9
Su'ega 99%
Fa'aaliga Pa'u pa'epa'e
CAS Nu. 10344-94-2
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Ola Fa'asa 2 tausaga
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