Hydrocortisone, 11β,17,21-trihydroxypregn-4-ene-3,20-dione, o le natura muamua GCin tagata.E ui lava i le tele o GCs faʻapipiʻi, hydrocortisone, ona esters, ma ona masima o loʻo tumau pea le autu o togafitiga faʻaonaponei adrenocortical steroid ma le tulaga masani mo le faʻatusatusaina o isi GCs ma MCs uma.Na faʻaaogaina mo faʻamatalaga uma na taʻua muamua.