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N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium masima CAS:66992-27-6
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt, lea e taʻua foi o HEPES sodium salt, o se vailaʻau vailaʻau e masani ona faʻaaogaina e fai ma sui o le pH i totonu o fale suʻesuʻe meaola ma vailaʻau.E fesoasoani e fa'amautu se tulaga mautu o le pH, fa'apena lelei mo fa'aoga e pei o le aganu'u fa'aola, su'esu'ega enzyme, su'esu'ega porotini, electrophoresis, ma vaila'au.HEPES sodium masima e fa'amautinoa tulaga sili ona lelei mo fa'agaioiga olaola ma fa'aleleia le sa'o ma le fa'amaoni o fa'ai'uga fa'ata'ita'iga.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9
2'-(4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium salt o se vailaʻau faʻasolosolo e masani ona faʻaaogaina i suʻesuʻega faʻamaʻi ma suʻesuʻega.Ose fa'aigoa fa'afefeteina o le sialic acid, o se ituaiga mole mole ga'o e maua i luga o sela.
O lenei faʻaogaina o loʻo faʻaaogaina e fai ma sui mo enzymes e taʻua o neuraminidases, lea e galue e aveese toega sialic acid mai glycoproteins ma glycolipids.Pe a galue nei enzymes i luga o le 2′-(4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium salt, e faʻasaʻo ai se oloa faʻafefe e taʻua o le 4-methylumbelliferone.
O le fluorescence e gaosia e le tuufaatasiga e mafai ona fuaina ma faʻatusatusa, tuʻuina atu faʻamatalaga e uiga i le gaioiga o enzymes neuraminidase.E aoga tele lenei i le suʻesuʻeina o faʻamaʻi eseese ma tulaga e fesoʻotaʻi ma aberrant sialic acid metabolism.
O loʻo faʻaogaina foʻi le faʻaogaina mo faʻamoemoega faʻamaonia, e pei o le suʻesuʻeina o faʻamaʻi pipisi e aofia ai le neuraminidase.I nei suʻesuʻega, o loʻo faʻaogaina le faʻaogaina e iloa ai le i ai o faʻamaʻi viral faʻapitoa poʻo le iloiloina o le aoga o le neuraminidase inhibitors i togafitiga faʻamaʻi.
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TAPSO CAS:68399-81-5 Tau Faumea
TAPSO (3-[N-tris(hydroxymethyl)methyl]amino]-2-hydroxypropanesulfonic acid) o se zwitterionic buffer e masani ona faʻaaogaina i suʻesuʻega faʻaola ma biochemical.Ose sui fa'apolopolo lelei ma le pKa latalata i le pH physiological, e talafeagai mo le fa'atumauina o se pH mautu i su'esu'ega fa'aola.O le TAPSO e masani ona faʻaaogaina i le faʻamamaina o porotini, suʻega enzyme, faʻasologa o le cell, ma le electrophoresis applications.O le maualuga o le solubility i le vai ma le maualalo o le faʻalavelave i gaioiga faʻaola e avea ai ma filifiliga lauiloa i le sosaiete faʻasaienisi.O le TAPSO e lauiloa ona o lona aafiaga itiiti i le gaioiga o le enzyme ma e masani ona faʻaaogaina e fai ma sui i isi mea faʻapipiʻi e pei o Tris poʻo phosphate buffers.
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N-Acetyl-L-cysteine CAS:616-91-1
O le N-Acetyl-L-cysteine (NAC) o se faʻasologa o le amino acid cysteine.E maua ai se puna o le cysteine ma e mafai ona faigofie ona liua i le tripeptide glutathione, o se antioxidant malosi i le tino.NAC ua lauiloa mo ona antioxidant ma mucolytic meatotino, faʻaaogaina i le tele o faʻaoga faʻalesoifua maloloina.
I le avea ai o se antioxidant, NAC fesoasoani e puipuia sela mai faʻaleagaina e mafua mai i faʻamaʻi saoloto, ituaiga okesene faʻafoʻi, ma toxins.E lagolagoina fo'i le glutathione synthesis, lea e iai sona sao taua i le fa'amamaina o le tino ma le fa'atumauina o le soifua maloloina o le tino.
Na suʻesuʻeina le NAC mo ona aoga aoga i le soifua maloloina o le manava, aemaise lava mo tagata taʻitoʻatasi e iai tulaga e pei o le bronchitis tumau, COPD, ma le cystic fibrosis.E masani ona faʻaaogaina e fai ma faʻamaʻi e fesoasoani i le manifinifi ma le faʻamavaeina o le mucus, e faigofie ai ona faʻamama le auala.
E le gata i lea, ua faʻaalia e le NAC le folafolaga i le lagolagoina o le soifua maloloina o le ate e ala i le fesoasoani i le aveeseina o mea oona, e pei o le acetaminophen, o se faʻamaʻi masani tiga.E ono iai fo'i a'afiaga puipuia mai le fa'aleagaina o le ate e mafua mai i le taumafaina o le 'ava malosi.
I le faaopoopo atu i lona antioxidant ma le manava lagolago meatotino, NAC ua suʻesuʻeina mo ona aoga aoga i le soifua maloloina o le mafaufau.O nisi suʻesuʻega e faʻaalia ai e ono iai se aafiaga lelei i faʻafitauli o le mafaufau, e pei o le atuatuvale ma le obsessive-compulsive disorder (OCD).
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PIPES CAS:5625-37-6 Tau Faumea
PIPES (piperazine-1,4-bisethanesulfonic acid) o se zwitterionic buffering compound e masani ona faʻaaogaina i suʻesuʻega o meaola ma meaola.Ose fa'amautu lelei pH ma se gafatia maualuga mo le fa'atumauina tulaga fa'amautu o le pH i le pH va'aiga o le 6.1 i le 7.5.O PIPES e itiiti le fa'alavelave i biomolecules ma e talafeagai mo su'ega fa'alagolago i le vevela.E masani ona faʻaaogaina i gel electrophoresis techniques ma vailaʻau faʻapitoa e fai ma sui faʻamautu.Ile aotelega, o le PIPES ose fa'aogaina tele ma fa'aaogaina lautele i fa'ata'ita'iga fa'apitoa.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
2',6'-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS ester o se vailaʻau vailaʻau faʻatasi ma se fausaga mole faʻalavelave.O lo'o i ai se vaega o le sulfopropylacridinium ma se vaega galue ester carboxylate.O le i ai o le ester moiety e faʻaalia ai e faʻaalia ma e mafai ona faʻaaogaina e fai ma faʻailoga poʻo se sui sui mo biomolecules.
Ole vaega ole sulfopropylacridinium o lo'o fa'ailoa mai e ono mafai ona fa'aoga ile su'esu'ega fa'atatau ile fluorescence, lea e mafai ona fa'aogaina e fai ma su'esu'ega felanulanua'i po'o vali mo le su'esu'eina ma le su'esu'eina o biomolecules.Atonu e iai fo'i le talafeagai i su'esu'ega o fa'agasologa feavea'i, e pei o le fa'ailoga o le calcium intracellular.
O le faʻaofiina o le vaega ester NHS e faʻaalia ai e mafai ona tali atu i amine muamua, e pei o mea o loʻo maua i polotini poʻo peptides, e fausia ai fusi amide mautu.O lenei fa'agaoioiga e fa'aogaina ai le fa'aogaina o le bioconjugation, lea e mafai ona fa'aoga e fa'ailoga pe suia ai biomolecules fa'atasi ai ma isi mole mole galue, e pei o fluorophores po'o pine.
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5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide CAS:4264-82-8
5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide o se faʻaogaina o loʻo faʻaaogaina i suʻesuʻega faʻapitoa o meaola, aemaise lava mo le suʻesuʻeina ma le vaʻaia o le gaioiga o le enzyme.O se mea'ai e mafai ona fa'afefeteina e enzymes fa'apitoa, e mafua ai le tu'uina atu o se mea lanu po'o se mea fa'alelei.
O lenei tuufaatasiga e masani ona faʻaaogaina i suʻega e iloa ai le i ai ma le gaioiga o enzymes pei ole beta-galactosidase ma beta-glucuronidase.O nei enzymes e faʻapipiʻiina le acetyl ma le glucosaminide vaega mai le meaʻai, e oʻo atu ai i le faʻavaeina o se chromophore lanumoana pe lanumeamata.
O le fausaga tulaga ese o le 5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide e mafai ai ona faigofie ona iloa ma faʻatusatusaina le gaioiga o le enzyme.O lona fa'aogaina i metotia fa'ata'ita'i eseese, e aofia ai le histochemistry, immunohistochemistry, ma su'esu'ega e fa'atatau i sela, ua saofagā i le malamalama atili i galuega ole enzyme.
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Masima masima masima CAS:139-41-3 Tau Faumea
N,N-Bis(2-hydroxyethyl)glycine sodium salt ose vaila'au fa'aogaina e fai ma sui fa'apolopolo i le tele o fa'aoga o meaola fa'aola ma biophysical.E fesoasoani e fa'amautu le maualuga o le pH i tulaga fa'ata'ita'i, e fa'aoga ai i su'esu'ega enzyme, su'esu'ega porotini, aganu'u sela, ma faiga fa'apolofesa i Sisifo.
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Spinosad CAS:131929-60-7 Faumea Faʻatau
O le Spinosad o se vaega 5 nicotinic acetylcholine receptor agonist, e mafua ai le faʻalavelave maso ma le gatete lona lua i le faʻagaoioia o le afi.O le fa'aumiumi ona fa'aalia e mafua ai le pipili ma le mate fle.Ole mate ole flea e amata ile 30 minute ole tui ma ile 4 itula e mae'a.Spinosad e le fegalegaleai ma nofoaga fusifusia o isi vailaʻau iniseti (GABA-ergic poʻo nicotinic).
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Rotenone CAS:83-79-4 Faumea Faumea
Rotenone ose manava ma fa'afeso'ota'i 'ona mo arthropods.O lona vave tu'itu'i gaioiga e mafua mai i le fa'aitiitia o le maua o le nicotinamide adenine dinucleotide e avea o se cofactor i auala eseese o meaola e aofia ai le Krebs cycle, ma fa'afefe ai le mitochondrial respiratory enzymes.
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Diazinon CAS:333-41-5 Faumea Faumea
O lo'o maua le Diazinon i le tulaga o se vai e leai ni lanu po'o se lanu enaena.E itiiti le solu i le vai ae matua solu i le suau'u eter, ava malosi, ma benzene.Diazinon e faʻaaogaina mo le puleaina o faʻatoʻaga eseese ma faʻamaʻi faʻamaʻi fale.E aofia ai fa'ama'i fa'ama'i i le 'ele'ele, i luga o la'au teuteu, fualaau 'aina, fualaau faisua, ma fa'ato'aga ma fa'ama'i fa'ama'i a le aiga e pei o lago, utu, ma mogamoga.
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Avermectin CAS:71751-41-2 Faumea Faumea
Abamectin (Avermectin) o se neura oona oona.O lona masini o loʻo faʻatatau i le GABAA faʻafeiloaʻi o le iniseti neuron synapse poʻo le neuromuscular synapse, faʻalavelave i le faʻaliliuina o faʻamatalaga o faʻaiʻuga o neura, e taʻua o le faʻaosofiaina o faʻaiʻuga o neura e faʻasaʻo ai le neurotransmitter inhibitor γ-aminobutyric acid (GA-BA), faʻaosofia le tatalaina lautele o le. GABA-gated chloride alalaupapa ma chloride alaala-faagaoioia aafiaga.
