2,2,2-TRIFLUOROETHYL TRIFLUOROACETATE CAS:407-38-5

O le 2,2,2-Trifluoroethyl trifluoroacetate (TFETA) o se vailaʻau e tele ona faʻaaogaina ma ona uiga faʻakemikolo tulaga ese e fesoasoani i lona aoga lautele i le tele o faʻaoga faʻapisinisi. O Meatotino O le TFETA e faʻailoaina i lona fausaga molecular, e aofia ai se trifluoroethyl group (-CF3CH2-) e faʻapipiʻi i se trifluoroacetate ester (-OC(O)CF3). O lenei tuʻufaʻatasiga e mafua ai se vai manino, leai se lanu ma se tulaga pupuna maualuga, e tusa ma le 145°C, ma le solubility sili ona lelei i solvents organic. O le vailaʻau e faʻaalia ai le maualalo o le reactivity ona o le natura electron-withdrawal o atoms fluorine, e tuʻuina atu ai le mautu malosi o vailaʻau i lalo o le tele o tulaga. O meatotino a le TFETA e talafeagai ai mo faʻaoga e manaʻomia ai le inertness, e pei o le faʻapipiʻiina o intermediates mautu ma ufiufi puipui. Faʻaoga Organic Synthesis: O le TFETA e avea o se intermediate taua i le organic synthesis, lea e auai ai i tali atu e faʻalauiloa ai galuega faatino fluorinated i totonu o molecules faigata. O lenei gafatia e taua tele i le kemisi faʻafomaʻi mo le fatuina o vailaʻau fluorinated ma le gaosiga o vailaʻau faʻapitoa lea e manaʻomia ai le faʻaleleia atili o le mautu ma le teteʻe atu i vailaʻau. Saienisi o Meafaitino: O le mautu o vailaʻau ma le mafai ona soloia o le TFETA e avea ai ma vaega lelei i le faʻatulagaina o ufiufi ma meafaitino e iai manaʻoga faʻapitoa mo le faʻatinoga. E faʻaaogaina e faʻaleleia atili ai le tumau ma meatotino puipuia o luga mai le faʻaleagaina o le siosiomaga ma osofaʻiga faʻakemikolo, e fesoasoani ai i le umi o le ola o meafaitino i faʻaoga e amata mai i ufiufi taʻavale i vaega eletise. Faʻaoga Faʻafomaʻi: O le matafaioi a le TFETA i le faʻaputuga faʻanatura e faʻalautele atu i faʻaoga faʻafomaʻi, lea e mafai ai e lona fausaga fluorinated ona faʻatonutonuina gaioiga faʻaola ma meatotino pharmacokinetic o molelaʻau faʻasaina. O lenei mea e avea ai ma meafaigaluega taua i le sailia o vailaʻau ma le atinaʻeina o faiga e faʻatatau i le faʻaleleia atili o le aoga o togafitiga ma le bioavailability. Faʻaputuga O le TFETA e faʻaputuina e ala i le esterification o le trifluoroacetic acid (CF3COOH) ma le 2,2,2-trifluoroethanol (CF3CH2OH) i lalo o tulaga acidic. O le tali atu e maua ai le TFETA faʻatasi ai ma le vai o se oloa e maua mai ai, lea e mafai ona faʻamamāina e ala i le faʻamamāina poʻo le solvent extraction e ausia ai le mama maualuga e talafeagai mo faʻaoga faʻapisinisi. O le faʻaputuga faigofie ma le taulimaina o le TFETA e fesoasoani i lona taugofie ma le faʻaaogaina lautele i vaega eseese e manaʻomia ai vailaʻau fluorinated. I se aotelega, o le 2,2,2-trifluoroethyl trifluoroacetate o se vailaʻau e tele ona aoga e taua i le gaosiga o mea ola, saienisi o meafaitino, ma le kemisi o vailaʻau. O ona uiga faʻakemikolo tulaga ese e mafai ai ona atiina ae meafaitino ma vailaʻau faʻapitoa faʻatasi ai ma le mautu faʻaleleia ma uiga faʻatino, ma faʻamamafaina ai lona taua i faʻaoga faʻapisinisi faʻaonaponei.