8-Bromo-3-methyl-xanthine CAS:93703-24-3

O le 8-bromo-3-methyl-xanthine, lea na faia i ni metotia fa'apitoa fa'alenatura, e iai sona fausaga fa'a-molecular tulaga ese e taua tele mo ana fa'aoga eseese. O le fa'avae o le xanthine, ua suia e le bromine ma methyl groups, e a'afia ai lona tali atu i vaila'au, solubility, ma fegalegaleaiga ma faiga fa'aola. O nei uiga fa'atulagaina e taua tele mo le malamalama i lona fa'asologa fa'afoma'i ma le gafatia fa'amalolo. Fa'aoga i Faletalavai O lenei vaila'au e iai le folafolaga i su'esu'ega fa'afoma'i ona o lona fausaga fa'atulagaina. O mea e maua mai i le Xanthine e lauiloa mo a latou gaioiga fa'afoma'i eseese, e aofia ai le avea ma phosphodiesterase inhibitors ma adenosine receptor antagonists. O le tu'ufa'atasiga fa'apitoa o le bromine ma methyl groups i luga o le 8-bromo-3-methyl-xanthine e mafai ona fa'aleleia atili ai lana gaioiga fa'aola ma a'afia ai lana auala e galue ai, ma avea ai ma sui tauva mo le atina'eina o vaila'au i le lumana'i e fa'atatau i fa'ama'i eseese. Gaoioiga Fa'aola ma Faiga O su'esu'ega e fa'aalia ai o mea e maua mai i le xanthine e fegalegaleai ma sini fa'aola e ala i auala e pei o le fa'atonutonuina o le enzyme ma le fusifusia o le receptor. O le bromine ma le methyl substitutions i luga o le 8-bromo-3-methyl-xanthine e mafai ona a'afia ai lona malosi, mautu o le metabolism, ma meatotino pharmacokinetic, e a'afia ai lona aoga ma le saogalemu i fa'aoga fa'amalolo. O le malamalama i nei faiga e taua tele mo le faʻaleleia atili o lona gafatia faʻamalolo. Auala Faʻapitoa ma Atinaʻe O le faʻatulagaina o le 8-bromo-3-methyl-xanthine e aofia ai faiga faʻaola faigata e amata mai le xanthine ma bromo-methylating agents. O le faʻaleleia atili o auala faʻapitoa e taua tele mo le ausiaina o le mama maualuga ma le fua, e taua tele mo le gaosiga faʻapisinisi ma faʻaoga faʻafomaʻi. O le faʻaleleia atili o auala faʻapitoa e faʻaleleia atili ai foʻi le taugofie ma le faʻaauauina i le mauaina ma le atinaʻeina o vailaʻau. Suʻesuʻega o loʻo iai nei ma Faʻatonuga i le Lumanai O taumafaiga suʻesuʻega o loʻo iai nei e taulaʻi i le suʻesuʻeina o gaioiga faʻapitoa o le vailaʻau, e aofia ai lona gafatia o se sui e teteʻe i le mumū poʻo lona aoga i togafitiga puipuia o neura. O suʻesuʻega i le lumanaʻi atonu e suʻesuʻeina ni suiga faʻatulagaina e faʻaleleia atili ai lona faʻamatalaga pharmacokinetic pe faʻaleleia atili ai le faʻapitoa i faʻamaʻi patino. E le gata i lea, o suʻesuʻega o loʻo faʻaauau pea e faʻamoemoe e faʻamaonia lona saogalemu ma le aoga e ala i iloiloga faʻapitoa ma suʻesuʻega faʻapitoa. Faaiuga I le faʻaiuga, o le 8-bromo-3-methyl-xanthine o loʻo faʻatusalia ai se vailaʻau taua i le kemisi faʻafomaʻi ma suʻesuʻega faʻafomaʻi ona o lona fausaga faʻapitoa faʻafomaʻi ma faʻaoga faʻafomaʻi. O lona tuʻufaʻatasia o le bromine ma methyl groups i totonu o se faʻavae xanthine e faʻamamafaina ai lona folafolaga faʻafomaʻi ma le tele o mea. O le faʻalauteleina o lo tatou malamalama i ana amioga faʻakemikolo, fegalegaleaiga faʻabiologika, ma auala faʻapitoa e taua tele mo le faʻaaogaina atoatoa o lona gafatia faʻamalolo ma faʻalauteleina ai ona faʻaoga i vailaʻau ma matāʻupu e fesoʻotaʻi i ai.