Avibactam sodium CAS:1192491-61-4

O le Avibactam sodium e faʻaaogaina i faiga faʻafomaʻi o se beta-lactamase inhibitor e toe faʻafoʻisia ai le aoga o nisi o vailaʻau faʻamaʻi e teteʻe atu i siama e teteʻe i vailaʻau eseese. E masani ona tuʻufaʻatasia ma vailaʻau faʻamaʻi e pei o le ceftazidime e fausia ai ni tuʻufaʻatasiga tumau e faʻatatau i se vaega lautele o siama Gram-negative, e aofia ai le Enterobacteriaceae ma le Pseudomonas aeruginosa. E fautuaina e le au fomaʻi vailaʻau faʻamaʻi e iai le avibactam sodium mo faʻamaʻi pipisi faigata i totonu o le manava, faʻamaʻi pipisi o le urinary tract, niumonia e maua i le falemaʻi, ma isi faʻamaʻi pipisi matuia e mafua mai i meaola e teteʻe atu i vailaʻau faʻamaʻi masani. O le faʻaopoopoina o le avibactam sodium e fesoasoani e faʻatoʻilalo ai auala teteʻe atu i siama, toe faʻafoʻisia ai le aoga o vailaʻau faʻamaʻi i le tau faʻasaga i faʻamaʻi pipisi e faigata ona togafitia. O faiga o fua e aofia ai le avibactam sodium e faʻatulagaina e faʻatatau i faʻamaʻi pipisi patino, mea e mafua ai le maʻi, taunuʻuga o suʻega o le vaivai, ma le tuʻufaʻatasiga o vailaʻau faʻamaʻi e faʻaaogaina. O le mataʻituina lelei o le tali atu i togafitiga, mamanu o le vaivai o siama, ma aʻafiaga leaga e ono tulaʻi mai e taua tele ina ia mautinoa ai taunuʻuga lelei o togafitiga ma faʻaitiitia ai le lamatiaga o le le manuia o togafitiga. O aʻafiaga leaga e fesoʻotaʻi ma vailaʻau faʻamaʻi e iai le avibactam sodium e ono aofia ai faʻalavelave i le gastrointestinal, tali atu i le maaleale, ma lamatiaga e fesoʻotaʻi ma le faʻaaogaina faʻatasi o vailaʻau faʻamaʻi. E tatau i foma'i ona mafaufau i uiga o tagata ta'ito'atasi ma fegalegaleaiga o vaila'au pe a fa'atonuina nei tu'ufa'atasiga ina ia fa'aleleia atili ai le aoga ma le saogalemu o togafitiga. I le tu'ufa'atasia o le avibactam sodium ma vaila'au fa'ama'i talafeagai, e mafai ai e foma'i ona fo'ia lelei fa'ama'i pipisi faigata e tete'e atu i vaila'au eseese, ma ofoina atu i tagata mama'i isi auala togafitiga ma fa'aleleia atili ai taunu'uga fa'aklinikal i le puleaina o fa'ama'i pipisi faigata.