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1 '1-Bis(diphenylphosphino)ferrocene Palladium(Ⅱ)chloride dichloromethane chloride CAS:95464-05-4
O le 1,1-Bis(diphenylphosphino)ferrocene Palladium(II) Chloride Dichloromethane Complex, fa'atasi ai ma le fua fa'akemikolo [Pd(dppf)Cl₂·CH₂Cl₂], o se fa'aputuga organometallic o lo'o i ai le palladium(II) e fa'atasi ma le dppf ligand ma chlorides i totonu o se dichloromethane solvent. E masani ona fa'aaogaina i le fa'aputuga fa'aola ma le catalysis.
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N-(6-bromopyridin-2-yl)thiourea CAS:439578-83-3
O le N-(6-Bromopyridin-2-yl)thiourea o se vailaʻau e faʻailoaina i le i ai o se vaega galue o le thiourea e pipii atu i se vaega 6-bromopyridin-2-yl. O lenei vailaʻau ua maua ai le fiafia i le kemisi faʻafomaʻi ona o ana gaioiga faʻafomaʻi eseese ma faʻaoga faʻapitoa mo togafitiga. O ona foliga tulaga ese o le fausaga e ofoina atu ai auala mo le mamanuina o ni vailaʻau fou ma ni sini faʻapitoa faʻapitoa, ma avea ai ma se aseta taua i le sailia ma le atinaʻeina o vailaʻau.
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2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL CAS:269409-97-4
O le 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, e masani ona ta'ua o le TMDBP, o se vaila'au fa'akemikolo e patino i le vasega o phenolic boronic esters. O lona fausaga molecular e aofia ai se vaega phenolic hydroxyl e pipii i se mama phenyl e iai se vaega o le cyclic ester o lo'o iai le boron. O lenei vaila'au e taua tele i le fa'aputuga o meaola, aemaise lava i gaioiga fa'apipi'i Suzuki-Miyaura, lea e avea ai o se mea taua tele mo le boronic ester. E le gata i lea, o lona fausaga mautu o le cyclic boronate ma lona natura e taofia ai le steric e aoga ai i le mamanuina o ligands mo gaioiga fa'asolosolo o le u'amea ma le atina'eina o mea faigaluega.
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1-Methyl-4-pyrazole boronic acid pinacol ester CAS:761446-44-0
O le 1-Methyl-4-pyrazole boronic acid pinacol ester o se vailaʻau faʻapitoa ua faʻavasegaina o se boronic ester. O lona fausaga molecular e aofia ai se vaega boronic acid e pipii i se mama pyrazole ua suia i se vaega pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). O lenei vailaʻau e taua tele i le faʻaputuga o meaola, aemaise lava i gaioiga faʻapipiʻi Suzuki-Miyaura, lea e avea ai o se reagent boronic ester e tele ona aoga. E le gata i lea, o lona mautu, le tali vave, ma le fetaui ma tulaga eseese o le tali atu e taua ai i le faʻaputuga o vailaʻau faʻapitoa, vailaʻau faʻatoʻaga, ma mea aoga.
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![Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG285.png)
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6
O le Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- o se vailaʻau faʻafefiloi bicyclic faʻatasi ai ma se fausaga autu o le cyclopenta[b]pyrrole ma se filifili itu hexahydro-1H-pyrrole-3a(1H)-methanol. O lenei molecule e taua tele i le kemisi faʻafomaʻi ona o ana gaioiga faʻafomaʻi e ono mafai ona faia. O lona fausaga tulaga ese e ofoina atu ai avanoa mo le atinaʻeina o ni sui tauva fou o vailaʻau, aemaise lava e taulaʻi i faʻalavelave faʻalemafaufau ma isi faʻamaʻi e taua tele ai le faʻatonutonuina o neurotransmitter receptors ma transporters. O le Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- e avea o se faʻavae mo le au faʻatau vailaʻau e suʻesuʻeina ni vailaʻau faʻafomaʻi fou faʻatasi ai ma meatotino faʻapitoa o le pharmacokinetic ma faʻaitiitia ai aʻafiaga.
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trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS:169248-97-9
O le Trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid o se mole mole lavelave e iai se mama pyrrolidine ua suia i se vaega tert-butoxycarbonyl i le tulaga 1 ma se vaega 3-(trifluoromethyl)phenyl i le tulaga 4. O lenei vailaʻau e taua tele i le kemisi faʻafomaʻi, ona o lona gafatia e avea o se vailaʻau faʻafomaʻi i le mamanuina o vailaʻau. O lona fausaga lavelave e maua ai avanoa mo le fatuina o ni vailaʻau faʻafomaʻi fou faʻatasi ai ma meatotino faʻafomaʻi faʻapitoa, aemaise lava e faʻatatau i auala e aʻafia ai faʻamaʻi mumū, kanesa, poʻo faʻalavelave o le tino tutotonu.
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(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1262849-90-0
O le (3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride o se vailaʻau faʻapitoa e faʻailoaina e se mama pyrrolidine ua suia i se vaega ethyl i le tulaga 3 ma se vaega tert-butyl i le tulaga 1. O lenei vailaʻau ua tosina mai ai le mafaufau i le kemisi faʻafomaʻi ona o lona faʻatulagaga stereochemical ma faʻaoga faʻafomaʻi e ono mafai ona faʻaaogaina. O lona faʻatulagaga tulaga ese e maua ai auala mo le mamanuina o ni vailaʻau fou ma ni sini faʻapitoa faʻapitoa, ma avea ai ma se aseta taua i le sailia o vailaʻau ma taumafaiga e atiina ae.
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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS: 1233501-65-9
O le Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride o se vailaʻau e iloga i le mama pyrrolidine ua suia i se vaega ethyl i le tulaga 3 ma se vaega tert-butyl i le tulaga 1. O lenei vailaʻau ua maua ai le gauai i le kemisi faafomaʻi ona o lona lavelave o le fausaga ma lona ono faʻaaogaina i vailaʻau. O lona faʻatulagaga tulaga ese e maua ai avanoa mo le mamanuina o vailaʻau fou ma ni sini faʻapitoa faʻapitoa, ma avea ai ma se aseta taua i le sailia o vailaʻau ma taumafaiga e atiina ae.
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4-Hydroxyphenylboronic acid pinacol ester CAS:269409-70-3
O le 4-Hydroxyphenylboronic acid pinacol ester, e ta'ua fo'i o le 4-HPBA pinacol ester, o se vaila'au fa'akemikolo e pa'ū i lalo o le vaega o boronic esters. O lona fausaga molecular e aofia ai se vaega boronic acid e pipii i se mama phenyl ua suia i se vaega pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). O lenei vaila'au e taua tele i le fa'aputuga fa'aola, aemaise lava i gaioiga fa'apipi'i Suzuki-Miyaura, lea e avea ai o se reagent boronic ester e tele ona fa'aoga. E le gata i lea, o lona mautu, faigofie ona taulimaina, ma le fetaui ma tulaga eseese o le tali atu e taua ai i le fa'aputuga o vaila'au fa'afoma'i, oloa fa'alenatura, ma mea aoga.
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![Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU259.png)
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5
O le Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride o se vailaʻau e aofia ai se vaega faʻatino o le carbamate e pipii i se mama piperidine ua suia i se vaega benzyl i le atomu nitrogen ma se vaega propyl i le atomu carbon. O lenei vailaʻau ua faʻaosofia ai le fiafia i le kemisi faʻafomaʻi ona o lona lavelave o le fausaga ma lona ono faʻaaogaina i vailaʻau. O lona faʻatulagaga tulaga ese e ofoina atu ai avanoa mo le mamanuina o vailaʻau fou ma ni sini faʻapitoa faʻapitoa, ma avea ai ma se aseta taua i le sailia o vailaʻau ma taumafaiga e atiina ae.
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9,9-Dimethyl-9H-fluoren-2-yl-boronic acid CAS:333432-28-3
O le 9,9-Dimethyl-9H-fluoren-2-yl-boronic acid, e masani ona ta'ua o le DMFBA, o se vaila'au fa'akemikolo e patino i le vasega o boronic acids. O lona fausaga molecular e iai se vaega boronic acid e fa'apipi'i i se fluorene scaffold ua suia i ni vaega methyl se lua i le tulaga 9. O lenei vaila'au e taua tele i le fa'aputuga o meaola, aemaise lava i gaioiga fa'apipi'i Suzuki-Miyaura, lea e galue ai o se vaila'au boronic acid e tele ona fa'aoga. E le gata i lea, o lona fausaga malosi ma le fa'apipi'iina e taua tele i le mamanuina o ligand mo gaioiga fa'asolosolo o u'amea ma le atina'eina o mea aoga.
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4-Carboxyphenylboronic acid CAS:14047-29-1
O le 4-Carboxyphenylboronic acid, e taʻua foʻi o le 4-Carboxyphenylboronic acid poʻo le 4-CPBA, o se vailaʻau faʻapitoa e patino i le vasega o boronic acids. E faʻailoaina i lona vaega faʻatino o le boronic acid (-B(OH)₂) e faʻapipiʻi i se mama phenyl ua suia i se vaega carboxylic acid (-COOH) i le tulaga para. O lenei vailaʻau e tele ona faʻaoga i le faʻaputuga faʻaola, aemaise lava i tali faʻapipiʻi Suzuki-Miyaura e fausia ai ni fusiua carbon-carbon. E le gata i lea, o lona gafatia e fusifusia i diols ma suka ua mafua ai ona faʻaaogaina i le atinaʻeina o sensors mo le siakiina o le glucose ma le kemisi faʻafomaʻi mo le mamanuina o enzyme inhibitors ma receptor ligands.
