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2-Hydroxyisonicotinic acid CAS:90-33-5
O le 2-Hydroxyisonicotinic acid o se mea e maua mai i le isonicotinic acid, e fa'ailoaina i le i ai o se vaega hydroxyl i le tulaga lona lua o le mama pyridine. O lenei vaila'au e fa'aalia ai le tele o gaioiga fa'aola, e aofia ai le ono mafai ona fa'asaga i siama ma fa'asaga i le mumū. O lona tutusa fa'atulagaga ma isi mea e maua mai i le nicotinic acid e avea ai ma sini manaia mo le atina'eina o vaila'au. Ua su'esu'eina e le au su'esu'e ona fa'aoga i le kemisi fa'afoma'i, aemaise lava i le togafitia o fa'ama'i eseese. O le vaila'au e avea o se poloka faufale mo le fa'aputuina o molela'au e sili atu ona lavelave ma ua maua ai le gauai i vaega o le fa'aputuga fa'aola ma su'esu'ega fa'afoma'i.
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Methyl 2-aminopyridine-4-carboxylate CAS:6937-03-7
O le Methyl 2-aminopyridine-4-carboxylate o se pyridine derivative e iai se amino group i le tulaga 2 ma se carboxylate ester i le tulaga 4, faatasi ai ma se methyl group e pipii i le carboxylic acid. O lenei vailaʻau e fiafia i ai i le kemisi faafomaʻi ona o ana gaioiga faʻaolaola e ono mafai ona faia, e aofia ai mea e teteʻe ai i siama ma mea e teteʻe ai i le mumū. O le faʻatulagaga tulaga ese o vaega faʻatino e faʻaleleia atili ai lona tali atu ma le aoga o se poloka faufale e tele ona aoga i le faʻaputuga o meaola. O loʻo faʻaauau pea suʻesuʻega i ona faʻaoga i le atinaʻeina o vailaʻau ma isi vaega, ma faʻaalia ai lona taua i totonu o le vaega o le heterocyclic chemistry.
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Tofacitinib Citrate CAS:540737-29-9
O le Tofacitinib citrate o se vailaʻau e taofia ai le Janus kinase (JAK) e faʻaaogaina mo le togafitia o le rheumatoid arthritis, psoriatic arthritis, ma le ulcerative colitis. E galue e ala i le taofia faʻapitoa o le JAK1 ma le JAK3 enzymes, lea e taua tele i auala faʻailoilo o cytokines eseese e aʻafia i faʻagasologa o le mumū. Faatasi ai ma le fua faʻatatau molecular C16H20N6O5S·C6H8O7, ua faʻaalia e le tofacitinib citrate le aoga i le faʻaitiitia o le mumū ma le faʻaleleia atili o le tulaga lelei o le olaga o tagata mamaʻi. Ua faʻamaonia mo le faʻaaogaina i falemaʻi i le tele o atunuʻu, o suʻesuʻega o loʻo faʻaauau pea e faʻamoemoe e suʻesuʻe ona faʻaoga lautele mo togafitiga, le saogalemu, ma taunuuga umi i le tele o faʻamaʻi autoimmune.
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Ta'avale CAS:294-90-6
O le Cyclen, po'o le 1,4,7,10-tetraazacyclododecane, o se vaila'au polyamine e iloga i lona fausaga fa'ata'amilosaga tulaga ese e fa'aalia ai atomu nitrogen e fa'apipi'iina i totonu o se mama e sefululua ona vaega. Fa'atasi ai ma le fua fa'atatau molecular C8H16N4, o le cyclen e avea o se ligand taua i le kemisi fa'amaopoopo ona o lona gafatia e fausia ai ni fa'alavelave mautu ma metala fesuia'i. O ona uiga chelating e taua ai i le tele o fa'aoga, e aofia ai le kemisi fa'afoma'i, radiopharmaceuticals, ma le kemisi supramolecular. O su'esu'ega faifai pea e su'esu'eina le gafatia o le cyclen i faiga fa'ao'oina o vaila'au ma le atina'eina o sui fa'ata'ita'i fa'atatau, ma fa'amamafa ai lona taua i saienisi fa'avae ma fa'aoga.
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![4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT317.png)
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5
O le 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane o se vailaʻau faʻaola bicyclic e iloga i lona fausaga tulaga ese o loʻo i ai ni fesoʻotaʻiga ether se lua ma ni atomu okesene se tolu i totonu o le faʻavae bicyclic. Faatasi ai ma le fua faʻatatau molecular C10H16O3, o lenei vailaʻau e faʻaalia ai ni meatotino faʻakemikolo manaia ona o le i ai o vaega methyl ma galuega faatino a le ether. O lona fausaga bicyclic e fesoasoani i lona mautu ma le tali atu, ma avea ai ma sui tauva mo le tele o faʻaoga i le kemisi faʻaola faʻapitoa. O suʻesuʻega e suʻesuʻeina lona faʻaaogaina i le faʻapipiʻiina o molelaʻau e sili atu ona faigata ma lona gafatia e avea o se poloka faufale i vailaʻau ma meafaitino faʻasaienisi.
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![4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1](https://cdn.globalso.com/xindaobiotech/VMLV8UWXAZ0XBLS6M290.png)
4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1
O le 4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine o se vailaʻau faʻapitoa e iloga i ona faʻaoga faʻafomaʻi. O loʻo i ai se fausaga tulaga ese e aofia ai le pyrrolopyrimidine core, o se chloro substituent, ma se sulfonyl moiety e fesoʻotaʻi ma se para-methylphenyl group. O lenei fausaga faʻatulagaina e mafai ona fesoasoani i lana gaioiga faʻaola, ma avea ai ma sui tauva mo suʻesuʻega i vaega e pei o le oncology poʻo le mumū. O loʻo faia suʻesuʻega e suʻesuʻe ai ana faiga o le gaioiga, aoga, ma le saogalemu, faʻatasi ai ma le sini o le faʻailoaina o ona faʻaoga faʻapitoa i tulaga faʻafomaʻi eseese.
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3-Pyridinesulfonyl chloride CAS:16133-25-8
O le 3-Pyridinesulfonyl chloride o se vailaʻau taua faʻaolaola e iai le fua faʻatatau molecular C6H6ClN O2S. O se sulfonyl chloride e maua mai i le pyridine, e iai le sulfonyl chloride functional group e faʻapipiʻi i le tulaga tolu o le mama pyridine. O lenei vailaʻau e faʻaaogaina muamua i le organic synthesis e fai ma reagent mo le faʻalauiloaina o sulfonyl groups i totonu o substrates eseese. O lona tali vave e mafai ai ona auai i tali o le nucleophilic substitution, ma avea ai ma mea taua i le faia o sulfonamides ma isi mole mole bioactive. E le gata i lea, o le 3-pyridinesulfonyl chloride e iai ona faʻaoga i vailaʻau ma agrochemicals.
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2-Aminoisonicotinic acid CAS:13362-28-2
O le 2-Aminoisonicotinic acid o se pyridine derivative, aemaise lava o se isomer o le nicotinic acid, e faʻailoaina i le i ai o se amino group i le 2-position o le isonicotinic acid structure. Faatasi ai ma le molecular formula C6H6N2O2, o lenei compound e faaalia ai ni meatotino faakemikolo manaia ma ua tosina atu ai le mafaufau i le kemisi faafomai ona o ana gaioiga faakemikolo e ono mafai ona faia, e aofia ai aafiaga e tetee atu ai i siama ma le mumū. O galuega faatino a le amino ma le carboxylic acid e mafai ai ona faia ni suiga eseese o kemikolo, ma avea ai ma se vaega taua i le organic synthesis. O loo faaauau pea ona suesueina e suesuega lona gafatia faafomai, ma faamamafaina ai lona taua i le atinaeina o fualaau faasaina ma isi faaaogaina.
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2-Amino-4-cyanopyridine CAS:42182-27-4
O le 2-Amino-4-cyanopyridine o se pyridine derivative e fa'ailoaina e se amino group i le tulaga 2 ma se cyano group i le tulaga 4 o le pyridine ring. Fa'atasi ai ma le molecular formula C6H4N4, o lenei fa'aputuga e fa'aalia ai ni meatotino fa'akemikolo mata'ina ma ni gaioiga fa'aolaola e ono mafai ona faia. Ua su'esu'eina mo ana fa'aoga i le kemisi fa'afoma'i, aemaise lava i le atina'eina o vaila'au ona o ona aafiaga e ono a'afia ai siama, siama, ma le mumū. O le iai o vaega fa'atino uma e lua e fa'aleleia atili ai lona tali atu, ma avea ai ma se vaega taua i le fa'aputuga fa'aola. O lo'o fa'aauau pea su'esu'ega e su'esu'e lona tele i vaega eseese e aofia ai vaila'au ma vaila'au fa'ato'aga.
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2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) CAS:399017-10-8
O le 2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) o se mea e maua mai i le thiazole, e iloga i lona fausaga tulaga ese e aofia ai le hydroxyl group, methyl group, ma le ethyl ester. O lenei vailaʻau ua maua ai le fiafia i le kemisi faafomaʻi ona o ana gaioiga faʻaolaola, e pei o meatotino e teteʻe ai i le mumū ma le antimicrobial. O le ituaiga masima hydrochloride e faʻaleleia atili ai le solubility ma le mautu, ma faʻafaigofie ai lona faʻaaogaina i faʻatulagaga faʻafomaʻi. O loʻo faʻaauau pea ona suʻesuʻeina e suʻesuʻega lona aoga i le tele o faʻaoga faʻafomaʻi, ma avea ai ma sui tauva taua mo nisi suʻesuʻega i le atinaʻeina o vailaʻau ma le faʻaleleia atili o le taʻitaʻi.
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3-Methyl-4-nitropyridine N-Oxide CAS:1074-98-2
O le 3-Methyl-4-nitropyridine N-oxide o se pyridine derivative e fa'ailoaina e se vaega methyl i le tulaga 3 ma se vaega nitro i le tulaga 4 o le mama pyridine, fa'atasi ai ma se vaega galue N-oxide. O lenei vaila'au e fa'aalia ai ni meatotino fa'akemikolo mata'ina ma gaioiga fa'aola, ma avea ai ma mea e fiafia i ai i vaega eseese e pei o le kemisi fa'afoma'i ma vaila'au fa'ato'aga. O le iai o vaega nitro ma N-oxide e mafai ona fa'aleleia atili ai lona tali atu ma fa'aoga talafeagai i le kemisi fa'apitoa. O lo'o fa'aauau pea su'esu'ega e su'esu'e le aoga o le vaila'au i le sailia o vaila'au ma isi fa'aoga, ma fa'aalia ai lona taua i le kemisi fa'aola i aso nei.
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(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine CAS:511534-44-4
O le (1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine o se vailaʻau chiral taua e iai le sulfonamide functional group ma le diphenylethylene backbone. Faatasi ai ma le molecular formula C16H20N2O2S, o lenei vailaʻau e iai sona sao taua i le asymmetric synthesis ma le catalysis ona o lona gafatia e fausia ai ni siosiomaga chiral mautu. O lona fausaga tulaga ese e mafai ai ona faia ni tali filifilia, ma avea ai ma mea taua i le atinaʻeina o vailaʻau ma agrochemicals. O suʻesuʻega faifai pea e suʻesuʻeina ana faʻaoga i le stereoselective synthesis, faʻamamafaina lona gafatia o se ligand i le organometallic chemistry ma faʻalauteleina lona taua i le organic synthesis faʻaonaponei.
