Ibandronate Sodium CAS:138844-81-2 Kamupani gaosi oloa

Ua fa'aaogaina le Ibandronate sodium e su'esu'e ai lona a'afiaga i le fa'ateleina ma le ultrastructure o Leishmania ma Giardia e ala i le gaosia o le concentration curves. Ua fa'aaogaina fo'i e fa'amanino ai le auala e ulufale ai le nitrogen-containing bisphosphonates (N-BPs) i totonu o le cytosol ma taofia ai la latou molecular target. O le Ibandronate sodium e taofia ai le farnesyl diphosphate synthase (IC50 = 20 nM). O le Ibandronate sodium fo'i o se mea e taofia ai le resorption o ponaivi. Ua su'esu'eina mo aafiaga in vitro anti-tumor, e pei o le apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, ma le inhibition of angiogenesis ma mo lona sao in vivo i le tele o kanesa e aofia ai le kanesa o le susu ma le prostate.